KeyEvent

https://ontology.toxindex.com/v1/KeyEvent AOP

A measurable change in biological state that is essential to the progression of one or more adverse outcome pathways. Whether it acts as a molecular initiating event, an intermediate event, or an adverse outcome is a role it plays within a pathway, not a property of the event itself.

Relationships

References

biological_events BiologicalEvent []

taxa Taxon []

Referenced By

AdverseOutcomePathway key_events

AdverseOutcomePathway molecular_initiating_events

AdverseOutcomePathway adverse_outcomes

KeyEventRelationship upstream

KeyEventRelationship downstream

Properties

Class properties with name, type, requirements, and description
Name	Type		Description
`key_event_id`	uri	required identifier	IRI of a key event: its identifiers.org IRI (https://identifiers.org/aop.events/{id}) when it is registered in the AOP-Wiki, otherwise a minted IRI.
`title`	string	required
`description`	string
`level_of_organization`	LevelOfOrganizationEnum		The level of biological organization at which a key event occurs.
`biological_events`	BiologicalEvent []		Structured statements of what changes in a key event.
`organs`	uri []		IRIs of the organs in which a key event occurs.
`sexes`	SexEnum []		Sexes for which a pathway, key event, or relationship holds.
`taxa`	Taxon []		The taxa for which a pathway, key event, or relationship holds.